Ketogenic Diet Kidney Stones Pubmed
Because carbonic anhydrase inhibitors and the ketogenic diet are each known risk factors for kidney stones simultaneous use of these therapies has been discouraged.
Ketogenic diet kidney stones pubmed. Without specific data the literature. While no studies report absolute renal damage associated with ketogenic diet use 6 of cases involving children with intractable epilepsy have reported the presence of kidney stones following eating the ketogenic diet for 1 5 years. Thirteen children 6 7 developed kidney stones. Ketogenic diet kd first proposed at the beginning of the last century is complex and has anticonvulsant effects yet not completely understood.
Long term use of the ketogenic diet in the treatment of epilepsy. Groesbeck dk bluml rm kossoff eh. The objective of this study was to establish the prevalence of nephrolithiasis in children in this combination therapy population. Dev med child neurol.
Kidney stones have been associated with use of the ketogenic diet in children with refractory seizure disorders. These children with renal calculi can be effectively treated with urine alkalinization and hydration while remaining on the ke togenic diet 14. We performed a case control study examining risk factors for the development of stones on the ketogenic diet and prospectively followed children initiating the ketogenic diet to evaluate the incidence of urolithiasis. Most studies that examine the adverse effects of ketogenic diets have been done in children with epilepsy.
The use of oral potassium citrate significantly decreased the prevalence of stones 3 2 vs 10 0 p 049 and increased the mean time on the ketogenic diet before a stone was first noted 260. Kidney stones carbonic anhydrase inhibitors and the ketogenic diet. The reported incidence of kidney stones in children on the ketogenic diet 5 4 is higher than that with carbonic anhydrase inhibitors alone 14. Risk factors and prevention.
The only known treatment of glucose transporter 1 deficiency syndrome glut 1 ds is a ketogenic diet kd which provides the brain with an alternative fuel. Over the last decades different types of ketogenic diets kds have been developed namely classical kd and modified atkins diet mad.